Dupuytren contracture

A Dupuytren contracture, or palmar fibromatosis, is a fibrosing condition that characteristically presents as a firm nodularity on the palmar surface of the hand with coalescing cords of soft tissue on the webs and digits.

It is considered the most common of the superficial fibromatoses and is thought to affect 1-2% of the population. People of northern European descent are typically affected with the highest prevalence in countries such as northern Scotland, Iceland, Norway, and Australia 2. Age at presentation usually peaks around 65. There may be an increased male predilection.

Associations

Additional diseases that are associated with palmar fibromatosis include

Patients typically present with palmar surface subcutaneous nodules on the of the distal crease of the hand. This may progresses to cords and bands and, finally, the characteristic flexion contracture secondary to fibrous attachments to the underlying tendon sheath.

It is progressive condition that causes shortening and thickening of the fibrous tissue of the palmar fascia.

Location
  • lesions can be bilateral in about half of cases 7
  • the 4th ray is typically involved 6
Ultrasound

Characterised as flat and poorly marginated hypoechoic nodules in the subcutaneous tissues superficial to flexor tendons. 

MRI

The lesions typically comprise of subcutaneous nodules, usually at the level of the distal palmar crease, and cords that lie parallel and superficial to the flexor tendons.

Signal characteristics of the cords include

Typical (~80% of cases) 1

  • T1: uniformly low signal intensity (similar to the signal intensity of tendon)
  • T2: uniformly low signal intensity (similar to the signal intensity of tendon)

Atypical 1

  • T1: low to intermediate signal intensity (a slightly higher signal intensity than that of tendon)
  • T2: low signal intensity 
Treatment and prognosis

A medical or surgical intervention may be required in patients suffering from a functional impairment (significant inability to use their hands for routine activities) or due to cosmetic embarrassment. Medical intervention includes triamcinolone, lidocaine, or collagenase injection. Vitamin E, gamma interferon, dimethyl sulfoxide, and splinting are not considered adequate treatments for Dupuytren's contracture. Surgical release of palmar fascia is usually indicated in patients with severe functional impairment and neurovascular deficit in a finger 8.  

It was originally described in 1831 by the French physician Dupuytren 2.

As a general differential for contracted fingers, consider other forms of contractures such as

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Article information

rID: 22918
Tag: cases
Synonyms or Alternate Spellings:
  • Palmar fibromatosis
  • Dupuytren's contracture
  • Dupuytren's contractures
  • Dupuytren contractures
  • Dupuytren's disease
  • Dupuytren disease

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Cases and figures

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    Dupuytren's contr...
    Case 1: on ultrasound
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