Dysmyelinating disorders

Dr Jeremy Jones et al.

Dysmyelinating disorders are a subset of white matter disorders characterised by abnormal myelination 1.

They are also known by the term leukodystrophy and are composed of a group of inherited conditions that are characterized by a defective structure and function of the myelin sheath 2. They are distinct from demyelinating disorders where there is destruction or damage of previously normal myelination. 

The use of two terms to refer to the same group of conditions is confusing and there is some variability in the use of terms between some authors.

For a discussion about this group of disorders, see the leukodystrophy article.

See also

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rID: 15595
Synonyms or Alternate Spellings:
  • Dysmyelinating diseases
  • Dysmyelinating disease
  • Dysmyelinating disorder

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