Dysphagia lusoria is an impairment of swallowing due to compression from an aberrant right subclavian artery (arteria lusoria).
Most patients with aberrant right subclavian arteries do not have symptoms. Some present with mild dysphagia, while a small minority have a severe enough disturbance in swallowing that leads to inability to swallow and severe nutritional problems.
In children, the most common presentations are stridor and recurrent chest infections, may be due to their tracheal softening comparing to adult population.
The diagnosis of dysphagia lusoria is always difficult and late as the symptoms are often nonspecific and in the same time, diagnostic endoscopy is negative in more than 50% cases, and manometry has no diagnostic role.
Compression of the oesophagus by the aberrant right subclavian artery can be exacerbated by atherosclerosis or aneurysmal dilatation.
Chest radiographs can demonstrate enlargement of the superior mediastinum.
Barium study of the oesophagus may show the indentation on the posterior esophageal wall by the artery.
CT angiography and MRI thorax are the best diagnostic modalities that could identify the arteria lusoria.
History and etymology
The word lusoria comes from the Latin phrase lusus naturae, meaning "freak of nature", which refers to the anomalous course of the artery 1.
As adult onset of dysphagia lusoria is rare, it should prompt evaluation for other reasons such as malignancy, vascular disease or gastro-oesophageal reflux disease (GORD) 3,4,5.
- 1. Bayford D. An Account of a Singular Case of Deglutition. Memoirs Med Soc London 1794; 2:271.
- 2. Levitt B, Richter JE. Dysphagia lusoria: a comprehensive review. Dis. Esophagus. 2007;20 (6): 455-60. doi:10.1111/j.1442-2050.2007.00787.x - Pubmed citation
- 3. Bittner RC, Roßdeutscher R: Leitfaden Radiologie. Gustav Fischer Verlag, Stuttgart, Jena, New York, 1996
- 4. Singh S, Grewal PD, Symons J et-al. Adult-onset dysphagia lusoria secondary to a dissecting aberrant right subclavian artery associated with type B acute aortic dissection. Can J Cardiol. 2008;24 (1): 63-5. Free text at pubmed - Pubmed citation
- 5. Puri S K, Ghuman S, Narang P, Sharma A, Singh S. CT and MR angiography in dysphagia lusoria in adults. Indian J Radiol Imaging 2005;15:497-501