Dystrophic soft tissue calcification is a type of soft-tissue calcification, which occurs in damaged or necrotic tissue, while the serum level of calcium and phosphorus are normal. It may progress to ossification, in which case a cortical and trabecular bone pattern is visible.
An often cited approach to developing a differential diagnosis is using the mnemonic VINDICATE, a form of surgical sieve:
- vascular
- infection
- granulomatous infection
- parasitic infestation
- cysticercosis
- dracunculiasis
- Armillifer armillatus
- neoplasm
- primary bone-forming tumors: osteosarcoma
- other sarcomas: specially synovial sarcoma
- osteoma
- tumor necrosis
- sarcoidosis 4
- drugs
- autoimmune
- dermatomyositis
- scleroderma and CREST syndrome
- systemic lupus erythematosus 3
- trauma
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