Citation, DOI, disclosures and article data
Citation:
Jones J, Bell D, Di Muzio B, et al. Empty amnion sign. Reference article, Radiopaedia.org (Accessed on 21 Jan 2025) https://doi.org/10.53347/rID-15186
The empty amnion sign is a sonographic observation where there is the visualization of an amniotic sac without concomitant visualization of an embryo. It is an indicator of pregnancy failure regardless of the mean sac diameter and is considered to have a sufficiently high positive predictive value 2.
See also
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1. McKenna K, Feldstein V, Goldstein R, Filly R. The Empty Amnion: A Sign of Early Pregnancy Failure. J Ultrasound Med. 1995;14(2):117-21. doi:10.7863/jum.1995.14.2.117
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2. Yegul N & Filly R. Further Observations on the Empty “amnion Sign”. J Clin Ultrasound. 2010;:NA. doi:10.1002/jcu.20673
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