Empty light bulb sign (brain death)

In brain death, on Tc-99m HMPAO imaging there is absent or reduced flow in the internal carotid arteries and increased flow within the external carotid arteries. This leads to absent uptake in the brain with subsequent increased perfusion in the nasal region. This appearance has been called the empty light bulb sign

It has also been described as the hot nose sign.

Article information

rID: 27841
Section: Signs
Synonyms or Alternate Spellings:
  • Empty skull sign
  • Empty light bulb sign

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Cases and figures

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