Encephalomalacia is term given to describe softening or loss of brain parenchyma with or without surrounding gliosis, as a late manifestation of injury. 

  • asymptomatic 
  • serve as a focus of seizure

Encephalomalacia is the end result of liquefactive necrosis of brain parenchyma following insult, usually occurring after cerebral ischemia, cerebral infection, hemorrhage, traumatic brain injury, surgery or other insults. It is not synonymous with gliosis, which is the proliferation of glial cells in response to injury.

Follows CSF signal on all sequences.

Article information

rID: 30580
Synonyms or Alternate Spellings:
  • Encephalomalacias

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Cases and figures

  • Case 1
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  • Case 2
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  • Case 3
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  • Case 4: multicystic encephalomalacia
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  • Case 5
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  • Case 6
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  • Case 7
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