Endochondral ossification

Last revised by Henry Knipe on 14 May 2020

Citation, DOI, disclosures and article data

Citation:

Mayhew P, Knipe H, Thurston M, et al. Endochondral ossification. Reference article, Radiopaedia.org (Accessed on 06 Dec 2023) https://doi.org/10.53347/rID-44009

DOI:

https://doi.org/10.53347/rID-44009

Permalink:

https://radiopaedia.org/articles/44009

rID:

44009

Article created:

2 Apr 2016, Pamela Mayhew

Disclosures:

At the time the article was created Pamela Mayhew had no recorded disclosures.

View Pamela Mayhew's current disclosures

Last revised:

14 May 2020, Henry Knipe ◉ ◈

Disclosures:

At the time the article was last revised Henry Knipe had no recorded disclosures.

View Henry Knipe's current disclosures

Revisions:

6 times, by 5 contributors - see full revision history and disclosures

Systems:

Musculoskeletal, Paediatrics

Sections:

Anatomy

Tags:

refs

Endochondral ossification describes the process of ossification from mesenchymal cells (stem cells) with a cartilaginous template and is involved in the healing process of fractures.

Bone formation occurs at ossification centers, which are either primary or secondary:

primary ossification centers are found in the central portion of the cartilaginous model and ossification advances towards the ends
secondary ossification centers are located at the epiphysis and apophysis