Enucleation

Last revised by Tariq Walizai on 18 Jun 2024

Enucleation of the eye describes the surgical removal of the entire globe with the separation of all connections to the orbit, including optic nerve transection. Alternatives such as evisceration or exenteration can be considered according to the underlying diagnosis and disease.

Rarely, auto-enucleation can occur, which is associated with psychosis in the majority of those cases.

Common indications for enucleation include 1:

Contraindications include the following ref:

  • intraocular malignancy with evidence of orbital spread

  • expected psychological trauma due to the loss of the eye

  • relatively in sympathizing eye

After obtaining written informed consent the procedure is done under general anesthesia with the conjunction of local anesthesia around the eyeball.

  • eyelid retraction with the lid speculum or a traction suture     

  • circumferential conjunctival peritomy and removal of Tenon fascia from the globe with blunt dissection between the rectus muscles

  • disinsertion of superior and inferior oblique muscles

  • optic nerve transection

  • minimize any orbital fat manipulation to reduce the risk of atrophy

Postoperative complications include the following ref:

  • hemorrhage

  • edema

  • infection

  • post-enucleation socket syndrome or anophthalmic syndrome

The imaging features described here are of normal postoperative appearance without developing complications or recurrent/residual disease processes.

CT or MRI will show the absence of the eye globe, optic nerve and adjacent contents of the orbital cavity in the form of asymmetry on the affected side along with changes in the height and transverse diameter of the optic chiasm ref.

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