Eosinophilia myalgia syndrome (EMS) is a fatal neurological condition caused by ingestion of improperly manufactured L-tryptophan. Impurities and/or metabolites that block histamine degradation result in peripheral blood eosinophilia and myalgia.
In the brain, cortical and basal ganglia atrophy with diffuse white matter abnormalities may be seen.
- Grossman RI, Yousem DM. Neuroradiology: The Requisites.