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Eosinophilic ureteritis (and eosinophilic pyelouerteritis) is a rare cause of ureteral inflammation. The clinical presentation and imaging features are non-specific.
Patients are usually atopic or hypereosinophilic with peripheral eosinophilia.
Associated with eosinophilic infiltration of other organs, including eosinophilic cystitis.
Histopathology shows a ureteral stricture with intense eosinophilic infiltrate. Some think that this entity was previously conflated with an older diagnosis of "idiopathic segmental ureteritis", but that the two entities are separate 1.
The condition usually manifests as a ureteral stricture. The imaging is otherwise non-specific.
- other etiologies for ureteral stricture
This is a rare diagnosis and should only be considered in the setting of a patient with a negative workup for urothelial carcinoma and tuberculosis, and with hypereosinophilia and possible eosinophilic involvement of other organs.
- 1. Spark RP, Gleason DM, DeBenedetti CD, Gigax JH. Is eosinophilic ureteritis an entity? 2 case reports and review. (1991) The Journal of urology. 145 (6): 1256-60. Pubmed
- 2. Uyama T, Moriwaki S, Aga Y, Yamamoto A. Eosinophilic ureteritis? Regional ureteritis with marked infiltration of eosinophils. (1981) Urology. 18 (6): 615-7. Pubmed
- 3. Singh JC, Karnik SV, Gopalakrishnan G. Eosinophilic ureteritis presenting as bilateral upper ureteric strictures. (2004) Scandinavian journal of urology and nephrology. 38 (3): 260-2. doi:10.1080/00365590410025523 - Pubmed