Epilepsy

A.Prof Frank Gaillard and Dr Henry Knipe et al.

Epilepsy is a common neurological disorder that has a varied presentation and requires two or more unprovoked seizures at least 24 hours apart for diagnosis. MRI is the modality of choice for epilepsy, most often investigating for an underlying cause, especially in adults. 

Epilepsy is very common, with ~3% of the population affected at some point in their life 1,5

Epilepsy syndromes can be generally divided into two broad categories 1,5:

  • generalised, e.g. absence epilepsy, tonic-clonic, myoclonic
  • partial (localisation-related), can progress to generalised

There is a wide range of causes, however, in adults with new onset of seizures ~50% will not have a determinable cause 1-5. The International League Against Epilepsy (ILAT) have proposed the following classification 6:

MRI is the modality of choice. Please see articles on specific conditions listed above for imaging features. There are a number of MRI protocols that can be used to investigate patients with seizures. 

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rID: 44318
Section: Gamuts
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Cases and figures

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    Case 1: tuberous sclerosis
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    Case 2: heterotopia / polymicrogyria
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    Case 3: gray matter heterotopia
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    Case 4: band heterotopia
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