Epithelioid trophoblastic tumor

Last revised by Francis Fortin on 25 May 2018

An epithelioid trophoblastic tumor (ETT) is an extremely rare form of trophoblastic neoplasm. It is considered as a rare subtype of gestational trophoblastic disease 2,4.

It typically presents in women of reproductive age (peak age in late 30's) and can occur between 1 and 18 years following a previous gestation 3.

It most commonly occurs in the uterus and usually (albeit remote) in association with a gestational event. Rare extra uterine locations have also been described which include

  • Fallopian tube
  • broad ligament 5

Serum beta-HCG levels are often highly elevated 4.

The clinical behavior of an ETT is often difficult to predict and while most cases follow a benign course following resection, there is a potential for metastatic disease 3.

ADVERTISEMENT: Supporters see fewer/no ads