Extrapontine myelinolysis (EPM) is one of the complications occurring secondary to rapid correction of hyponatraemia, and is, along with central pontine myelinolysis encompassed by the more recent term osmotic demyelination syndrome.
In the vast majority of cases it is associated with central pontine myelinolysis but it can also (rarely) occur as an isolated entity.
In extrapontine myelinolysis, sites of involvement include:
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