Extrapontine myelinolysis

Last revised by Dr Daniel J Bell on 12 Jun 2021

Extrapontine myelinolysis (EPM) is one of the complications occurring secondary to rapid correction of hyponatremia, and is, along with central pontine myelinolysis encompassed by the more recent term osmotic demyelination syndrome.

In the vast majority of cases it is associated with central pontine myelinolysis but it can also (rarely) occur as an isolated entity.

Pathology

Location

In extrapontine myelinolysis, sites of involvement include:

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Cases and figures

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