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Extrapulmonary tuberculosis (TB) refers to the hematogenous spread of Mycobacterium tuberculosis.
Extrapulmonary tuberculosis can occur as a primary form of the disease, i.e. direct infection of an extrapulmonary organ without the presence of primary pulmonary tuberculosis or it can occur as a result of the spread of primary pulmonary tuberculosis.
It appears classically as tuberculous granulomata (tuberculomas) within the affected organs. However, certain forms of the disease exist manifesting with specific findings:
- head and neck
- gastrointestinal tuberculosis
- tuberculous peritonitis
- tubercular lymphadenopathy
- visceral tuberculosis
- hepatic tuberculosis
- gallbladder tuberculosis
- pancreatic tuberculosis
- splenic tuberculosis
- genitourinary tuberculosis
Widely variable dependent on the site of involvement. It is best to refer to site-specific articles.
As tuberculous organ infection can mimic malignant disease recent studies have reported the usefulness of 18FDG PET-CT in evaluating and following up patients in whom the diagnosis is in doubt 4.
- 1. Lee JY. Diagnosis and treatment of extrapulmonary tuberculosis. Tuberc Respir Dis (Seoul). 2015;78 (2): 47-55. doi:10.4046/trd.2015.78.2.47 - Free text at pubmed - Pubmed citation
- 2. Horsburgh CR, Barry CE, Lange C. Treatment of Tuberculosis. N. Engl. J. Med. 2015;373 (22): 2149-60. doi:10.1056/NEJMra1413919 - Pubmed citation
- 3. Skoura E, Zumla A, Bomanji J. Imaging in tuberculosis. Int. J. Infect. Dis. 2015;32: 87-93. doi:10.1016/j.ijid.2014.12.007 - Pubmed citation
- 4. Vorster M, Sathekge MM, Bomanji J. Advances in imaging of tuberculosis: the role of ¹⁸F-FDG PET and PET/CT. Curr Opin Pulm Med. 2014;20 (3): 287-93. doi:10.1097/MCP.0000000000000043 - Pubmed citation