Face of the giant panda sign (midbrain)
Last revised by Francis Deng on 18 May 2020
Citation, DOI, disclosures and article data
Citation:
Gaillard F, Deng F, Weerakkody Y, et al. Face of the giant panda sign (midbrain). Reference article, Radiopaedia.org (Accessed on 05 Oct 2024) https://doi.org/10.53347/rID-4439
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rID:
4439
Article created:
Disclosures:
At the time the article was created Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosures
Last revised:
18 May 2020,
Francis Deng ◉
Disclosures:
At the time the article was last revised Francis Deng had no recorded disclosures.
View Francis Deng's current disclosures
Revisions:
11 times, by
8 contributors -
see full revision history and disclosures
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Synonyms:
- Panda sign of the midbrain
- Panda face sign (Wilson disease)
The face of the giant panda sign in neuroimaging refers to the appearance of the midbrain, when the red nucleus and substantia nigra are surrounded by high T2 signal in the tegmentum.
It is classically seen in Wilson disease, although whenever the white matter is diffusely abnormal in the region a similar appearance will be perceived such as in Japanese encephalitis.
See also
- panda sign of sarcoidosis
- double panda sign in Wilson disease
References
- 1. Schott JM. A neurological MRI menagerie. Pract Neurol. 2007;7 (3): 186-90. doi:10.1136/jnnp.2007.120261 - Pubmed citation
- 2. Hitoshi S, Iwata M, Yoshikawa K. Mid-brain pathology of Wilson's disease: MRI analysis of three cases. J. Neurol. Neurosurg. Psychiatr. 1991;54 (7): 624-6. Free text at pubmed - Pubmed citation
- 3. Stefano Zagami A, Boers PM. Disappearing "face of the giant panda". Neurology. 2001;56 (5): 665. Pubmed citation
- 4. Thapa R, Ghosh A. 'Face of the giant panda' sign in Wilson disease. Pediatr Radiol. 2008;38 (12): 1355. doi:10.1007/s00247-008-1017-4 - Pubmed citation
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