Familial atypical multiple mole melanoma syndrome
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At the time the article was created Yuranga Weerakkody had no recorded disclosures.View Yuranga Weerakkody's current disclosures
At the time the article was last revised Daniel J Bell had no recorded disclosures.View Daniel J Bell's current disclosures
Familial atypical multiple mole melanoma (FAMMM) syndrome is an autosomal dominant genodermatosis characterized by multiple melanocytic nevi (often more than 50) and a family history of melanoma.
It is associated with mutations in the CDKN2A gene and shows reduced penetrance and variable expressivity.
Some FAMMM patients show an increased risk for the development of pancreatic adenocarcinoma and possibly other malignancies.