Fat containing liver lesions represent a variety of benign and malignant liver lesions may contain macroscopic and/or intracytoplasmic fat in sufficient quantities enabling characterization on imaging studies. Most fat-containing liver lesions (80%) in patients with cirrhosis are malignant, most of which are hepatocellular carcinoma 3.
Differential diagnosis
Benign
- focal fatty change
- hepatic angiomyolipoma
- focal nodular hyperplasia
- hepatic lipoma
- pseudolipoma of the Glisson capsule
- xanthomatous lesion of Langerhans cell histiocytosis (LCH)
- hepatic adenoma
- hepatic teratoma / hepatic dermoid
- hepatic adrenal rest tumor: can rarely have malignant transformation
- post-operative: pack using omental tissue
- tamoxifen-induced reversible steatosis
- hepatic myelolipoma
Malignant
- hepatocellular carcinoma
- primary or secondary liposarcoma
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