The differential of a fat containing solitary pulmonary nodule is very narrow.
In a well circumscribed smooth or lobulated mass (especially if it has been largely stable in size over time) presence of fat is essentially pathognomonic of a pulmonary hamartoma, and usually not further assessment is required.
The more complete list of pulmonary nodules that may contain fat includes:
- pulmonary hamartoma: by far the commonest
- myelolipoma of lung
- metastatic disease
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- 2. Gaerte SC, Meyer CA, Winer-muram HT et-al. Fat-containing lesions of the chest. Radiographics. 2002;22 Spec No : S61-78. Radiographics (link) - Pubmed citation