The differential of a fat containing solitary pulmonary nodule is very narrow. The presence of fat within a nodule, indicated by a measured density between -30 and -150 HU, is a reliable sign of benignity 1,3.
In a well circumscribed smooth or lobulated mass (especially if it has been largely stable in size over time) presence of fat is essentially pathognomonic of a pulmonary hamartoma, and usually, no further assessment is required.
The more complete list of pulmonary nodules that may contain fat includes:
pulmonary hamartoma: by far the commonest 3
lipoma 3
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metastatic disease
See also
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fat-containing solitary pulmonary nodule
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