The differential of a fat containing solitary pulmonary nodule is very narrow.
In a well circumscribed smooth or lobulated mass (especially if it has been largely stable in size over time) presence of fat is essentially pathognomonic of a pulmonary hamartoma, and usually not further assessment is required.
The more complete list of pulmonary nodules that may contain fat includes:
- pulmonary hamartoma: by far the commonest
- metastatic disease
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