Fat redistribution syndrome
Features include :
- hypertrophy in the neck fat pad (buffalo hump)
- increased fat in the abdominal region (protease paunch)
- loss of fat in the midface and extremities.
Biochemically, these patients have increased triglycerides, total cholesterol, low-density lipoprotein-cholesterol, and extremely low high-density lipoprotein-cholesterol.
If left untreated, these patients develop and die of complications of metabolic origin such as cardiovascular diseases or diabetes. Biochemical features manifest before the clinical pictures become apparent.
For hypertrophy of the fat around the neck consider:
- Madelung disease
- steroid use
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