Fatty mediastinal masses (differential)

A.Prof Frank Gaillard et al.

Fatty mediastinal masses are relatively uncommon, and the differential diagnosis is brief, including 1-4:

  • lipoma
  • liposarcoma
  • thymolipoma
  • benign mature teratoma
  • lipoblastoma
  • extravasation of lipid-rich hyperalimentation fluid 3
  • fibrofatty replacement of the central portion of mediastinal lymph nodes can be seen as the sequelae of previous inflammatory disease 3
  • pulmonary hamartoma may abut the mediastinum
  • neurofibroma can have fat attenuation on CT, however the fatty changes in neurofibroma are rarely observed.5

Additionally a number of conditions can result in accumulation or herniation of normal fat into the mediastinum, mimicking a mass.

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Article information

rID: 22333
System: Chest
Section: Gamuts
Synonyms or Alternate Spellings:
  • Fatty mediastinal masses
  • Fatty mediastinal lesions
  • Fatty mediastinal mass
  • Fatty mediastinal lesion
  • Fat containing mediastinal masses (differential diagnosis)
  • Fat contianing mediastinal lesion

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Cases and figures

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    Case 1: thymolipoma (likely)
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    Case 2: lipoma
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    Case 3: mediastinal liposarcoma
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