Fetal conditions associated with maternal diabetes

Last revised by Francis Fortin on 16 Oct 2019

Citation, DOI, disclosures and article data

Citation:

Weerakkody Y, Fortin F, Hacking C, et al. Fetal conditions associated with maternal diabetes. Reference article, Radiopaedia.org (Accessed on 01 Jul 2024) https://doi.org/10.53347/rID-9204

DOI:

https://doi.org/10.53347/rID-9204

Permalink:

https://radiopaedia.org/articles/9204?iframe=true

rID:

9204

Article created:

24 Mar 2010, Yuranga Weerakkody ◉

Disclosures:

At the time the article was created Yuranga Weerakkody had no recorded disclosures.

View Yuranga Weerakkody's current disclosures

Last revised:

16 Oct 2019, Francis Fortin

Disclosures:

At the time the article was last revised Francis Fortin had no recorded disclosures.

View Francis Fortin's current disclosures

Revisions:

4 times, by 4 contributors - see full revision history and disclosures

Systems:

Obstetrics

Synonyms:

Conditions associated with maternal diabetes

There are numerous fetal congenital anomalies associated with maternal diabetes.

They include

cardiac: congenital cardiac anomalies
- ventricular septal defect (VSD) ⁵
- conotruncal anomalies
  - transposition of the great arteries (TGA)
  - truncus arteriosus
- fetal congestive cardiac failure (without any structural cardiac anomaly) ⁵
- fetal hypertrophic cardiomyopathy ⁸
pulmonary
- surfactant deficiency ²
- transient tachypnea of the newborn (TTN) ²
central nervous system
- neural tube defects ⁷
- encephalocoeles
- holoprosencephaly ¹
- caudal regression syndrome ³
- sirenomelia
- spina bifida
gastrointestinal
- situs anomalies
- meconium plug syndrome ⁴
renal
- renal agenesis ⁵
- fetal hydronephrosis ⁵
- ureteric duplication ⁵
skeletal
others
- polyhydramnios
- large for dates fetus
- fetal macrosomia
- intra-uterine growth restriction (IUGR): when the maternal diabetes severe there can be a paradoxical IUGR as opposed to fetal macrosomia
- single umbilical artery

References

1. Takanashi J, Barkovich AJ, Clegg NJ et-al. Middle interhemispheric variant of holoprosencephaly associated with diffuse polymicrogyria. AJNR Am J Neuroradiol. 2003;24 (3): 394-7. AJNR Am J Neuroradiol (full text) - Pubmed citation
2. Duara S, Spackman TJ, Boutwell WC et-al. A newly recognized profile in neonatal lung disease with maternal diabetes. AJR Am J Roentgenol. 1985;144 (3): 529-33. AJR Am J Roentgenol (abstract) - Pubmed citation
3. Stroustrup smith A, Grable I, Levine D. Case 66: caudal regression syndrome in the fetus of a diabetic mother. Radiology. 2004;230 (1): 229-33. doi:10.1148/radiol.2301020942 - Pubmed citation
4. Amodio J, Berdon W, Abramson S et-al. Microcolon of prematurity: a form of functional obstruction. AJR Am J Roentgenol. 1986;146 (2): 239-44. AJR Am J Roentgenol (abstract) - Pubmed citation
5. Dunn V, Nixon GW, Jaffe RB et-al. Infants of diabetic mothers: radiographic manifestations. AJR Am J Roentgenol. 1981;137 (1): 123-8. AJR Am J Roentgenol (abstract) - Pubmed citation
6. Becerra JE, Khoury MJ, Cordero JF et-al. Diabetes mellitus during pregnancy and the risks for specific birth defects: a population-based case-control study. Pediatrics. 1990;85 (1): 1-9. Pediatrics (abstract) - Pubmed citation
7. Dheen ST, Tay SS, Boran J et-al. Recent studies on neural tube defects in embryos of diabetic pregnancy: an overview. Curr. Med. Chem. 2009;16 (18): 2345-54. Curr. Med. Chem. (link) - Pubmed citation
8. Elmekkawi SF, Mansour GM, Elsafty MS, Hassanin AS, Laban M, Elsayed HM. Prediction of Fetal Hypertrophic Cardiomyopathy in Diabetic Pregnancies Compared with Postnatal Outcome. (2015) Clinical medicine insights. Women's health. 8: 39-43. doi:10.4137/CMWH.S32825 - Pubmed

Fetal conditions associated with maternal diabetes

Citation, DOI, disclosures and article data

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