Fetal hydronephrosis represents the abnormal dilatation of the fetal renal collecting system, with pelvi-ureteric junction obstruction the most commonly encountered cause.
Please, refer to the article on fetal pyelectasis for a dedicated discussion on this relatively common and usually benign form of mild hydronephrosis.
Although there is an overlap of definition between pyelectasis and hydronephrosis, the former has been widely used instead of mild hydronephrosis given that the great majority of the cases represent only a physiological incidental finding that resolves spontaneously, while the latter tends to be reserved for cases where a pathological obstruction is suspected.
Depending on its definition, the estimated prevalence may range between 1-3% of pregnancies.
Marked hydronephrosis (particularly in the 3rd trimester) can result from a number of pathologies, which include:
- posterior urethral valves: in males
- congenital pelvi-ureteric junction obstruction: the commonest cause of fetal hydronephrosis ref
- congenital vesico-ureteric junction obstruction
- urethral agenesis
- congenital megaloureter
- megacystis microcolon syndrome
- megacystis megaureter syndrome 7
- fetal vesico-ureteric reflux
- prune-belly syndrome (rare)
In the second trimester, the severity of fetal hydronephrosis may be graded as 1-2.
- mild hydronephrosis: anteroposterior renal pelvic diameter measures ≥5 mm (≥4 mm at 16-20 weeks)
- moderate/severe hydronephrosis: anteroposterior renal pelvic diameter measures ≥7 mm or if there is associated calyceal dilatation
- persistent hydronephrosis: ≥10 mm in the 3rd trimester
Ancillary sonographic features:
dilatation of the renal calyces
- dilated ureter if the obstruction is distal
- concurrent oligohydramnios if there is a bilateral obstruction (or unilateral obstruction with significantly impaired renal function in the other kidney)
Treatment and prognosis
Management will depend on the underlying pathology. The degree of renal pelvic dilatation correlates with the outcome. A renal pelvic anteroposterior diameter of 9 mm or more, and a pelvic-to-renal anteroposterior diameter ratio of 0.45 before 32 weeks of gestation and 0.52 thereafter are considered to be useful for the detection of a severe outcome postnatally 3.
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- 7. Twining P, McHugo JM, Pilling DW. Textbook of fetal abnormalities. Elsevier Health Sciences. (2007) ISBN:044307416X. Read it at Google Books - Find it at Amazon