Fetal intracranial calcification refers to intracranial calcification detected in utero. This can arise from a number of pathologies which include:
-
fetal toxoplasmosis infection: calcification tends to be randomly distributed
fetal cytomegalovirus infection1: calcification tends to be periventricular in distribution
calcifications are much less in herpes simplex and rubella infection
intracranial tumours associated with calcification: intracranial teratoma
-
certain phakomatoses
Sturge-Weber syndrome: gyriform pattern of cortical calcifications
tuberous sclerosis: rare to have calcification present in utero
sequelae of an in utero intracranial haemorrhage
-
postnatal infections
Radiographic features
Ultrasound
Calcification tends to manifest as brightly echogenic foci within the fetal brain.