Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Yap J, Jones J, et al. Fetal middle cerebral arterial Doppler assessment. Reference article, Radiopaedia.org (Accessed on 19 Jan 2025) https://doi.org/10.53347/rID-13681
Fetal middle cerebral arterial (MCA) Doppler assessment is an important part of assessing fetal cardiovascular distress, fetal anemia or fetal hypoxia. In the appropriate situation it is a very useful adjunct to umbilical artery Doppler assessment. It is also used in the additional work up of:
Doppler ultrasound
For an accurate measurement, the fetal head should be in the transverse plane. An axial section of the brain, including the thalami and the sphenoid bone wings, should be obtained and magnified. The MCA vessels are often found with color or power Doppler ultrasound overlying the anterior wing of the sphenoid bone near the base of the skull. The reading should be obtained close to its origin in the internal carotid artery as the systolic velocity decreases with distance from the point of origin of this vessel. An angle of insonation of <15° should be used; typically, an angle that approximates 0° can be achieved by moving the transducer on the maternal abdomen.
Parameters used include:
ADVERTISEMENT: Supporters see fewer/no ads
- in the normal situation the fetal MCA has a high resistance flow which means there is minimal antegrade flow in fetal diastole
- in pathological states this can turn into a low resistance flow mainly as a result of the fetal head sparing theory
- paradoxically in some situations such as with severe cerebral edema, the flow can revert back to a high resistance pattern when the pathology has not yet resolved - this is a very poor prognostic sign
- cerebroplacental ratio: >1:1 is normal and <1:1 is abnormal
- it can occasionally show end-diastolic flow reversal, a non-pathological finding that is usually due to increased intracranial pressure mostly by probe compression 2,3
-
1. Mari G & Hanif F. Fetal Doppler: Umbilical Artery, Middle Cerebral Artery, and Venous System. Semin Perinatol. 2008;32(4):253-257. doi:10.1053/j.semperi.2008.04.007
-
2. Baschat A, Gembruch U, Harman C. The Sequence of Changes in Doppler and Biophysical Parameters as Severe Fetal Growth Restriction Worsens. Ultrasound Obstet Gynecol. 2001;18(6):571-577. doi:10.1046/j.0960-7692.2001.00591.x
-
3. Moise K. The Usefulness of Middle Cerebral Artery Doppler Assessment in the Treatment of the Fetus at Risk for Anemia. Am J Obstet Gynecol. 2008;198(2):161.e1-161.e4. doi:10.1016/j.ajog.2007.10.788
-
4. Fong K, Ohlsson A, Hannah M et al. Prediction of Perinatal Outcome in Fetuses Suspected to Have Intrauterine Growth Restriction: Doppler US Study of Fetal Cerebral, Renal, and Umbilical Arteries. Radiology. 1999;213(3):681-689. doi:10.1148/radiology.213.3.r99dc08681
-
5. Suzuki S, Sawa R, Yoneyama Y, Otsubo Y, Araki T. Fetal Middle Cerebral Artery Doppler Waveforms in Twin–Twin Transfusion Syndrome. Gynecol Obstet Invest. 1999;48(4):237-240. doi:10.1159/000010190
-
6. Abdel-Fattah S, Soothill P, Carroll S, Kyle P. Middle Cerebral Artery Doppler for the Prediction of Fetal Anaemia in Cases Without Hydrops: A Practical Approach. BJR. 2002;75(897):726-730. doi:10.1259/bjr.75.897.750726
-
7. Rodeck, Charles H., Whittle, Martin J.. Fetal Medicine: Basic Science and Clinical Practice. (2009) ISBN: 9780443104084
-
8. Gita Ganguly Mukherjee, Surveen Chakravarty. Current Obstetrics and Gynaecology [FOGSI]. (2007) ISBN: 8180619966
-
9. Bahado-Singh R, Kovanci E, Jeffres A et al. The Doppler Cerebroplacental Ratio and Perinatal Outcome in Intrauterine Growth Restriction. Am J Obstet Gynecol. 1999;180(3):750-756. doi:10.1016/s0002-9378(99)70283-8
-
10. Bano S, Chaudhary V, Pande S, Mehta V, Sharma A. Color Doppler Evaluation of Cerebral-Umbilical Pulsatility Ratio and Its Usefulness in the Diagnosis of Intrauterine Growth Retardation and Prediction of Adverse Perinatal Outcome. Indian Journal of Radiology and Imaging. 2010;20(01):20-25. doi:10.4103/0971-3026.59747
-
11. Baschat A & Gembruch U. The Cerebroplacental Doppler Ratio Revisited. Ultrasound Obstet Gynecol. 2003;21(2):124-127. doi:10.1002/uog.20
-
12. Komwilaisak R, Saksiriwuttho P, Ratanasiri T, Kleebkaow P, Seejorn K. Pulsatility Index of the Middle Cerebral Artery in Normal Fetuses. J Med Assoc Thai. 2004;87 Suppl 3:S34-7. PMID 21213492
-
13. Respondek M, Woch A, Kaczmarek P, Borowski D. Reversal of Diastolic Flow in the Middle Cerebral Artery of the Fetus During the Second Half of Pregnancy. Ultrasound Obstet Gynecol. 1997;9(5):324-329. doi:10.1046/j.1469-0705.1997.09050324.x
-
14. Kaluarachchi A, Jayawardena G, Ranaweera A, Rishard M. Hyperechoic Amniotic Fluid in a Term Pregnancy. J Family Med Prim Care. 2018;7(3):635. doi:10.4103/jfmpc.jfmpc_83_18
Promoted articles (advertising)