Fetal thrombocytopaenia

Fetal thrombocytopaenia refers to an abnormally low platelet count in the fetus. The acceptable normal range for a fetal platelet count is similar to adults and do not vary significantly with gestation age. The lower limit for cut off is therefore usually taken as:

  • 150,000/uL for thrombocytopaenia and
  • 50,000/uL for severe thrombocytopaenia

It is most often caused by maternal alloantibodies against fetal platelets crossing the placenta and resulting in platelet destruction. This condition, known as fetal and neonatal alloimmune thrombocytopenia (FNAIT) is considered a platelet equivalent of Rh isoimmunisation 5.

Other causes include:

Associations

Recognised associations include:

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Article information

rID: 15164
System: Obstetrics
Tag: cases
Synonyms or Alternate Spellings:
  • Fetal thrombocytopenia

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