Fetal thrombocytopenia
Updates to Article Attributes
Title
was changed:
Fetal thrombocytopaeniathrombocytopenia
Body
was changed:
Fetal thrombocytopaeniathrombocytopenia refers to an abnormally low platelet count in the fetus. The acceptable normal range for a fetal platelet count is similar to adults and do not vary significantly with gestation age. The lower limit for cut off is therefore usually taken as:
- 150,000/uL for
thrombocytopaeniathrombocytopenia and - 50,000/uL for severe
thrombocytopaeniathrombocytopenia
Pathology
It is most often caused by maternal alloantibodies against fetal platelets crossing the placenta and resulting in platelet destruction. This condition, known as fetal and neonatal alloimmune thrombocytopenia (FNAIT) is considered a platelet equivalent of Rh isoimmunisation 5.
Other causes include:
- in utero infection(s)
- placental insufficiency
-
idiopathic
thrombocytopaenicthrombocytopenic purpura (ITP)
Associations
Recognised associations include:
- radial ray anomalies
- placental chorioangioma 3
- maternal autoimmune
thrombocytopaenicthrombocytopenic purpura: the fetus tends to developthrombocytopaeniathrombocytopenia in ~40-70% of cases 1.
Complications
See also
-<p><strong>Fetal thrombocytopaenia</strong> refers to an abnormally low platelet count in the fetus. The acceptable normal range for a fetal platelet count is similar to adults and do not vary significantly with gestation age. The lower limit for cut off is therefore usually taken as:</p><ul>-<li>150,000/uL for thrombocytopaenia and</li>-<li>50,000/uL for severe thrombocytopaenia</li>- +<p><strong>Fetal thrombocytopenia</strong> refers to an abnormally low platelet count in the fetus. The acceptable normal range for a fetal platelet count is similar to adults and do not vary significantly with gestation age. The lower limit for cut off is therefore usually taken as:</p><ul>
- +<li>150,000/uL for thrombocytopenia and</li>
- +<li>50,000/uL for severe thrombocytopenia</li>
-<a href="/articles/idiopathic-thrombocytopaenic-purpura">idiopathic thrombocytopaenic purpura</a> <a href="/articles/itp">(ITP)</a>- +<a href="/articles/idiopathic-thrombocytopaenic-purpura">idiopathic thrombocytopenic purpura</a> <a href="/articles/itp">(ITP)</a>
-<a href="/articles/radial-ray-anomaly">radial ray anomalies </a><ul><li><a href="/articles/tar-syndrome">TAR syndrome</a></li></ul>- +<a href="/articles/radial-ray-anomaly">radial ray anomalies </a><ul><li><a href="/articles/tar-syndrome">TAR syndrome</a></li></ul>
-<li>maternal autoimmune thrombocytopaenic purpura: the fetus tends to develop thrombocytopaenia in ~40-70% of cases <sup>1</sup>.</li>- +<li>maternal autoimmune thrombocytopenic purpura: the fetus tends to develop thrombocytopenia in ~40-70% of cases <sup>1</sup>.</li>
Updates to Synonym Attributes
Title
was changed:
Fetal thrombocytopeniathrombocytopaenia