Fetal thrombocytopenia
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was changed:
A fetalFetal thrombocytopaenia refers to an abnormally low platelet count in the fetus. The acceptable normal range for a fetal platelet count is similar to adults and do not vary significantly with gestation age. The lower limit for cut off is therefore usually taken as:
- 150,000
/ uL/uL for thrombocytopaenia and - 50,000
/ uL/uL for severe thrombocytopaenia
Pathology
It is most often caused by maternal alloantibodies against fetal platelets crossingthe placenta and resulting in platelet destruction. This condition, known asfetal and neonatal alloimmune thrombocytopenia (FNAIT) is considered a platelet equivalent of Rh isoimmunisation 5.
Other causes include:
Associations
Recognised associations include:
- radial ray anomalies
- placental chorioangioma 3
- maternal autoimmune thrombocytopaenic purpura: the fetus tends to develop thrombocytopaenia in
~ 40 - 70~40-70% of cases 1.
Complications
See also
-<p>A<strong> fetal thrombocytopaenia</strong> refers to an abnormally low platelet count in the fetus. The acceptable normal range for a fetal platelet count is similar to adults and do not vary significantly with gestation age. The lower limit for cut off is therefore usually taken as </p><ul>-<li>150,000 / uL for thrombocytopaenia and</li>-<li>50,000 / uL for severe thrombocytopaenia</li>-</ul><h4>Pathology</h4><p>It is most often caused by maternal alloantibodies against fetal platelets crossing-the placenta and resulting in platelet destruction. This condition, known as-fetal and neonatal alloimmune thrombocytopenia (FNAIT) is considered a platelet equivalent of Rh isoimmunisation <sup>5</sup>.</p><p>Other causes include</p><ul>-<li><a href="/articles/in-utero-infection" title="In utero infection">in utero infection(s)</a></li>-<li><a href="/articles/placental-insufficiency" title="Placental insufficiency">placental insufficiency</a></li>- +<p><strong>Fetal thrombocytopaenia</strong> refers to an abnormally low platelet count in the fetus. The acceptable normal range for a fetal platelet count is similar to adults and do not vary significantly with gestation age. The lower limit for cut off is therefore usually taken as:</p><ul>
- +<li>150,000/uL for thrombocytopaenia and</li>
- +<li>50,000/uL for severe thrombocytopaenia</li>
- +</ul><h4>Pathology</h4><p>It is most often caused by maternal alloantibodies against fetal platelets crossing the placenta and resulting in platelet destruction. This condition, known as fetal and neonatal alloimmune thrombocytopenia (FNAIT) is considered a platelet equivalent of Rh isoimmunisation <sup>5</sup>.</p><p>Other causes include:</p><ul>
- +<li><a href="/articles/in-utero-infection">in utero infection(s)</a></li>
- +<li><a href="/articles/placental-insufficiency">placental insufficiency</a></li>
-<a href="/articles/idiopathic-thrombocytopaenic-purpura" title="idiopathic thrombocytopaenic purpura">idiopathic thrombocytopaenic purpura</a> <a href="/articles/itp" title="(ITP)">(ITP)</a>- +<a href="/articles/idiopathic-thrombocytopaenic-purpura">idiopathic thrombocytopaenic purpura</a> <a href="/articles/itp">(ITP)</a>
-</ul><h5>Associations</h5><p>Recognised associations include</p><ul>- +</ul><h5>Associations</h5><p>Recognised associations include:</p><ul>
-<a href="/articles/radial-ray-anomaly" title="Radial ray anomalies">radial ray anomalies </a><ul><li><a href="/articles/tar-syndrome" title="TAR syndrome">TAR syndrome</a></li></ul>- +<a href="/articles/radial-ray-anomaly">radial ray anomalies </a><ul><li><a href="/articles/tar-syndrome">TAR syndrome</a></li></ul>
-<a href="/articles/placental-chorioangioma" title="Placental chorioangioma">placental chorioangioma</a> <sup>3</sup>- +<a href="/articles/placental-chorioangioma">placental chorioangioma</a> <sup>3</sup>
-<li>maternal autoimmune thrombocytopaenic purpura : the fetus tends to develop thrombocytopaenia in ~ 40 - 70% of cases <sup>1</sup>.</li>-</ul><h4>Complications</h4><ul><li><a href="/articles/fetal-intracranial-haemorrhages" title="fetal intracranial haemorrhages">fetal intracranial haemorrhages</a></li></ul><h4>See also</h4><ul><li><a href="/articles/fetal-anaemia" title="Fetal anaemia">fetal anaemia</a></li></ul>- +<li>maternal autoimmune thrombocytopaenic purpura: the fetus tends to develop thrombocytopaenia in ~40-70% of cases <sup>1</sup>.</li>
- +</ul><h4>Complications</h4><ul><li><a href="/articles/fetal-intracranial-haemorrhages">fetal intracranial haemorrhages</a></li></ul><h4>See also</h4><ul><li><a href="/articles/fetal-anaemia">fetal anaemia</a></li></ul>