Last revised by Henry Knipe on 24 Apr 2023

Fibrosarcomas are malignant tumors of fibroblast origin. They are a type of soft tissue sarcoma that can be grouped by patient age, i.e. adult fibrosarcoma and infantile fibrosarcoma, and/or anatomical region, for example:

These tumors are of mesenchymal origin.

On histopathology, they are typically described as having "herringbone" architecture. Tumors may be well-differentiated or poorly differentiated.

On CT, masses with similar density to muscle may indicate a fibrosarcoma.

Although detectable on MRI, fibrosarcoma is currently (c. 2020) not universally understood to have a distinct signature MRI appearance that is the same regardless of the anatomical region.

Although adult and infantile fibrosarcomas are histologically the same, the prognoses are different with children having more favorable outcomes 4.

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.