Fibrosarcoma of the breast

Dr Henry Knipe and Radswiki et al.

Fibrosarcoma of the breast is a type of malignant stromal sarcoma that rarely occurs as a primary tumour within the breast. 

Pathology

A fibrosarcoma is composed of immature mesenchymal elements surrounded by a collagenous substance. It is a type of breast sarcoma with a predominant “herringbone” growth pattern created by elongated spindle cells arranged in broad interdigitating sheets, bands, or fascicles. Some fibrosarcomas lack this classic herringbone pattern and consist instead of a more loosely structured fibroblastic proliferation. 

Radiographic features

Mammography

Fibrosarcomas are often seen as a non-spiculated, dense breast mass with largely indistinct borders, although some borders may be sharp. There are no specific mammographic features distinguish these from round breast carcinomas or non-calcified fibroadenomas 1.

Breast imaging and pathology
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Article information

rID: 15152
Systems: Breast, Oncology
Section: Pathology
Synonyms or Alternate Spellings:
  • Fibrosarcoma of breast
  • Primary fibrosarcoma of the breast
  • Breast fibrosarcoma
  • Primary breast fibrosarcoma

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