Fibrosarcoma of the breast
Citation, DOI, disclosures and article data
At the time the article was created The Radswiki had no recorded disclosures.View The Radswiki's current disclosures
At the time the article was last revised Yaïr Glick had no recorded disclosures.View Yaïr Glick's current disclosures
Fibrosarcoma of the breast is a type of malignant stromal sarcoma that rarely occurs as a primary tumor within the breast.
A fibrosarcoma is composed of immature mesenchymal elements surrounded by a collagenous substance. It is a type of breast sarcoma with a predominant “herringbone” growth pattern created by elongated spindle cells arranged in broad interdigitating sheets, bands, or fascicles. Some fibrosarcomas lack this classic herringbone pattern and consist instead of a more loosely structured fibroblastic proliferation.
Fibrosarcomas are often seen as a non-spiculated, dense breast mass with largely indistinct borders, although some borders may be sharp. There are no specific mammographic features to distinguish these from round breast carcinomas or non-calcified fibroadenomas 1.
- 1. Elson BC, Ikeda DM, Andersson I et-al. Fibrosarcoma of the breast: mammographic findings in five cases. AJR Am J Roentgenol. 1992;158 (5): 993-5. AJR Am J Roentgenol (abstract) - Pubmed citation
- 2. Lee JY, Kim DB, Kwak BS et-al. Primary fibrosarcoma of the breast: a case report. J Breast Cancer. 2011;14 (2): 156-9. doi:10.4048/jbc.2011.14.2.156 - Free text at pubmed - Pubmed citation
- 3. Payan HM, England DM. Fibrosarcoma mimicking breast fibromatosis. Am J Med Genet Suppl. 1987;3 : 257-62. - Pubmed citation
- 4. Santamaría G, Velasco M, Bargalló X et-al. Radiologic and pathologic findings in breast tumors with high signal intensity on T2-weighted MR images. Radiographics. 2010;30 (2): 533-48. doi:10.1148/rg.302095044 - Pubmed citation