Fibrosarcomas are malignant tumors of fibroblast origin. They are a type of soft tissue sarcoma that can be grouped by patient age, i.e. adult fibrosarcoma and infantile fibrosarcoma, and/or anatomical region, for example:
On histopathology, they are typically described as having "herringbone" architecture. Tumors may be well-differentiated or poorly differentiated.
Radiographic features
CT
On CT, masses with similar density to muscle may indicate a fibrosarcoma.
MRI
Although detectable on MRI, fibrosarcoma is (c. 2020) not universally understood to have a distinct signature MRI appearance that is the same regardless of the anatomical region.
Treatment and prognosis
Although adult and infantile fibrosarcomas are histologically the same, the prognoses are different with children having more favorable outcomes 4.
1. Baheti A, O'Malley R, Kim S et al. Soft-Tissue Sarcomas: An Update for Radiologists Based on the Revised 2013 World Health Organization Classification. AJR Am J Roentgenol. 2016;206(5):924-32. doi:10.2214/AJR.15.15498 - Pubmed
2. Wang, Hexiang, Nie, Pei, Dong, Cheng, Li, Jie, Huang, Yonghua, Hao, Dapeng, Xu, Wenjian. CT and MRI Findings of Soft Tissue Adult Fibrosarcoma in Extremities. (2020) BioMed Research International. 2018: 6075705. doi:10.1155/2018/6075705 - Pubmed
4. Sargar K, Sheybani E, Shenoy A, Aranake-Chrisinger J, Khanna G. Pediatric Fibroblastic and Myofibroblastic Tumors: A Pictorial Review. Radiographics. 2016;36(4):1195-214. doi:10.1148/rg.2016150191 - Pubmed