Fibroxanthoma of bone

Last revised by Assoc Prof Craig Hacking on 24 Jul 2018

Fibroxanthoma of bone is a confusing term that is sometimes used to encompass non-ossifying fibroma and fibrous cortical defect, and at other times synonymously with just non-ossifying fibromas. As non-ossifying fibroma and fibrous cortical defect are histologically the same, and differ only in size (non-ossifying fibroma >2-3 cm) it is safe to not lose too much sleep over this one.

The term metaphyseal fibrous defect is probably a safer collective term for the two entities.

Fibrous cortical defect and non-ossifying fibroma are very common, seen in up to 30-40% of skeletally immature children/adolescents 3.

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Cases and figures

  • Fig 1: distribution
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