Fluid-fluid level containing bone lesions

Last revised by Henry Knipe on 1 Sep 2022

Fluid-fluid level containing bone lesions are best seen on MRI, although with narrow window width they can also be appreciated on CT.


Their prevalence is estimated at ~3% of bone and soft tissue tumors 1.

Differential diagnosis

Their presence is non-specific, as they are seen in both benign and malignant lesions:

There is a mnemonic for fluid-fluid levels on MRI.

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