Fracture non-union describes the failure of normal fracture healing processes. It occurs when both the periosteal and endosteal healing responses stop, resulting in no formation of bridging bone 2. Solid bone healing will not occur without further treatment or intervention.
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Terminology
There is no consensus definition in the radiology or orthopedic literature, however, FDA (USA) defines it as a fracture with a minimum of at least nine months since the initial injury with no signs of healing for the final three months 1.
Radiographic features
There are different types of fracture non-union with various imaging characteristics:
hypertrophic: abundant callus formation; radiolucent line (unmineralized fibrocartilage) at the non-union site
oligotrophic: little or no callus formation; diastasis at the fracture site
atrophic: bony surfaces partially resorbed; no callus formation; osteopenia; sclerotic avascular bone segments; segmental bone loss
infected: osteolysis; osteopenia; sclerotic avascular bone segments; segmental bone loss
synovial pseudoarthrosis: variable appearance (hypertrophic, oligotrophic, or atrophic)