Fracture non-union

Last revised by Sonam Vadera on 3 Jan 2025

Fracture non-union describes the failure of normal fracture healing processes. It occurs when both the periosteal and endosteal healing responses stop, resulting in no formation of bridging bone 2. Solid bone healing will not occur without further treatment or intervention.

There is no consensus definition in the radiology or orthopedic literature, however, FDA (USA) defines it as a fracture with a minimum of at least nine months since the initial injury with no signs of healing for the final three months 1.

There are different types of fracture non-union with various imaging characteristics:

  • hypertrophic: abundant callus formation; radiolucent line (unmineralized fibrocartilage) at the non-union site

  • oligotrophic: little or no callus formation; diastasis at the fracture site

  • atrophic: bony surfaces partially resorbed; no callus formation; osteopenia; sclerotic avascular bone segments; segmental bone loss

  • infected: osteolysis; osteopenia; sclerotic avascular bone segments; segmental bone loss

  • synovial pseudoarthrosis: variable appearance (hypertrophic, oligotrophic, or atrophic)

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.