Fraser syndrome

Last revised by Andrew Murphy on 18 Aug 2019

Fraser syndrome is an extremely rare congenital syndromic anomaly. 

The estimated incidence is at around 0.04:10,000 live-born infants and 1:10,000 stillbirths.

The syndromic spectrum can comprise of:

It carries an autosomal recessive inheritance with an abnormal gene locus at 4p21.

It is named after George R Fraser, a British human geneticist who first described the features of the syndrome in 1962.

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Cases and figures

  • Case 1: craniofacial dysmorphism
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  • Case 1: syndactyly
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