The free/total PSA ratio (%fPSA) is an additional new parameter used in assessing PSA levels. Some authors 1,2 recommend that men with PSA levels of 4.1 to 10 ng/mL who are not suspected of having prostate cancer by whatever means should undergo %fPSA measurement and then be carefully monitored at short intervals over the long term if they have lower %fPSA levels.
It should be taken into account that %fPSA will be elevated in men on dialysis treatment 3.
- 1. Thakur V, Singh PP, Talwar M, Mukherjee U. Utility of free/total prostate specific antigen (f/t PSA) ratio in diagnosis of prostate carcinoma. Disease markers. 19 (6): 287-92. Pubmed
- 2. Veneziano S, Pavlica P, Compagnone G, Martorana G. Usefulness of the (F/T)/PSA density ratio to detect prostate cancer. Urologia internationalis. 74 (1): 13-8. doi:10.1159/000082702 - Pubmed
- 3. Bruun L, Björk T, Lilja H, Becker C, Gustafsson O, Christensson A. Percent-free prostate specific antigen is elevated in men on haemodialysis or peritoneal dialysis treatment. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 18 (3): 598-603. Pubmed