Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Bell D, Glick Y, et al. Free/total PSA ratio. Reference article, Radiopaedia.org (Accessed on 24 Apr 2024) https://doi.org/10.53347/rID-55701
The free/total PSA ratio (%fPSA) is an additional new parameter used in assessing prostate specific antigen (PSA) levels. It is the simple mathematical ratio of the free PSA in the serum over the total PSA in the serum and is expressed as a dimensionless quantity 4.
Some authors 1,2 recommend that men with PSA levels of 4.1 to 10 ng/mL who are not suspected of having prostate cancer by whatever means should undergo free/total PSA ratio measurement and then be carefully monitored at short intervals over the long term to see if the ratio declines.
It should be taken into account that free/total PSA ratio will be elevated in men on dialysis treatment 3.
See also
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1. Thakur V, Singh PP, Talwar M, Mukherjee U. Utility of free/total prostate specific antigen (f/t PSA) ratio in diagnosis of prostate carcinoma. Disease markers. 19 (6): 287-92. Pubmed
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2. Veneziano S, Pavlica P, Compagnone G, Martorana G. Usefulness of the (F/T)/PSA density ratio to detect prostate cancer. Urologia internationalis. 74 (1): 13-8. doi:10.1159/000082702 - Pubmed
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3. Bruun L, Björk T, Lilja H, Becker C, Gustafsson O, Christensson A. Percent-free prostate specific antigen is elevated in men on haemodialysis or peritoneal dialysis treatment. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 18 (3): 598-603. Pubmed
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4.Prcic A, Begic E, Hiros M. Actual Contribution of Free to Total PSA Ratio in Prostate Diseases Differentiation. (2016) Medical archives (Sarajevo, Bosnia and Herzegovina). 70 (4): 288-292. doi:10.5455/medarh.2016.70.288-292 - Pubmed
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