Friedrich disease is an eponymous name for osteonecrosis of the sternal end of the clavicle. It is a rare condition and documentation in the medical literature is scarce with most case reports dating from before 1990.
It is more often encountered in children and adolescents 1.
Radiograph and CT
Diffuse sclerosis of the clavicular head of the clavicle is the main finding 1,2. A central notch-like defect in the center of sternoclavicular articulation has also been described 1.
It appears to be mostly a self-limited condition that can resolve spontaneously and responds to conservative treatment 1-3.
The general differentials consideration are those of a sclerotic clavicle.
- 1. RO Cone, D Resnick, TG Goergen, C Robinson, V Vint, P Haghighi. Condensing osteitis of the clavicle. (2012) American Journal of Roentgenology. 141 (2): 387-8. doi:10.2214/ajr.141.2.387 - Pubmed
- 2. Macule F, Ferreres A, Palliso F, Prat S, Ramon R. Aseptic necrosis of the sternal end of the clavicle Friedrich's disease. (1990) Acta orthopaedica Belgica. 56 (3-4): 613-5. Pubmed
- 3. Shimizu K, Awaya G, Matsuda F, Wakita S, Mayekawa M. Friedrich's disease: a case report. (1991) Nihon geka hokan. Archiv fur japanische Chirurgie. 60 (3): 184-8. Pubmed