Fundic gland polyp

Dr Andrew Ryan and Dr Henry Knipe et al.

Fundic gland polyps (FGP) are the most common type of gastric polyp.

FGPs occur most commonly in middle-aged females. They have been reported to be identified in ~1% of gastroscopies 3,4

FGPs are usually an asymptomatic, incidental finding 1

FGPs account for ~60% (range 47-77%) of gastric polyps 1-3. They may arise sporadically or be part of the syndrome (e.g. familial adenomatous polyposis), although there are different genetic mutations between sporadic and FAP-associated cases 1,2

The pathogenesis remains unclear, and there may be an association with antacid medications (e.g. proton pump inhibitors) and reduced rates of Helicobacter pylori infections. 

FGPs arise in the gastric body and fundus, and are sessile, measuring <10 mm (normally 1-5 mm) in size. They may be multiple or single 1-4.

FGPs are benign with no malignant potential 4

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Article information

rID: 40691
Section: Pathology
Synonyms or Alternate Spellings:
  • Cystic fundic gland polyps
  • Fundic gland polyps (FGP)
  • Sporadic fundic gland polyposis (SFGP)
  • Fundic gland polyposis in patients without FAP
  • Fundic gland polyps

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Cases and figures

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