Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Bell D, Jones J, et al. Fungal osteomyelitis. Reference article, Radiopaedia.org (Accessed on 23 Apr 2024) https://doi.org/10.53347/rID-75588
Fungal osteomyelitis is an uncommon form of osteomyelitis that often occur concurrently with septic arthritis.
Clinical presentation
They generally tend to present in an indolent fashion.
Pathology
Fungal bone and joint infections result from direct inoculation, contiguous infection spread, or hematogenous seeding of organisms. The most common offending organisms include 1
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Candida spp. e.g. Candida albicans
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Aspergillus spp.
Other uncommon agents include
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Histoplasma spp.
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Blastomyces spp.
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Coccidioides spp
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Cryptococcus spp.
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Sporothrix spp.
Location
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C. albicans, vertebral osteomyelitis is considered the most common location in adults, whereas femoral and humeral bones are typically involved in pediatric patients 4
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Aspergillus spp., vertebral bodies and ribs are considered most frequently involved 4
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1. Bariteau J, Waryasz G, McDonnell M, Fischer S, Hayda R, Born C. Fungal Osteomyelitis and Septic Arthritis. J Am Acad Orthop Surg. 2014;22(6):390-401. doi:10.5435/JAAOS-22-06-390 - Pubmed
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2. Kohli R & Hadley S. Fungal Arthritis and Osteomyelitis. Infect Dis Clin North Am. 2005;19(4):831-51. doi:10.1016/j.idc.2005.08.004 - Pubmed
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3. Urs A, Singh H, Mohanty S, Sharma P. Fungal Osteomyelitis of Maxillofacial Bones: Rare Presentation. J Oral Maxillofac Pathol. 2016;20(3):546. doi:10.4103/0973-029X.190966 - Pubmed
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4. Gamaletsou M, Walsh T, Sipsas N. Epidemiology of Fungal Osteomyelitis. Curr Fungal Infect Rep. 2014;8(4):262-70. doi:10.1007/s12281-014-0200-3
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