Gadobutrol

Dr Dan J Bell and Dr Matt A. Morgan et al.

Gadobutrol (also known as Gadovist/GadavistTM) is an extracellular intravenous contrast agent used in magnetic resonance imaging.

  • cyclic, non-ionic molecule 
  • 100% renally excreted
  • T1 relaxivity @ 1.5 T: 4.9-5.5 (slightly higher than other extracellular contrast agents)
  • concentration: 1.0 mmol/ml
  • recommended dosage: 0.1 mmol/kg

Of note, gadobutrol's standard concentration (1 mmol/ml) is 2x - 4x than that of other commercially-available gadolinium chelates, and the smaller injection volume should be considered when planning the timing of the arterial phase in post-contrast dynamic sequences.

Indications

As an extracellular contrast agent, gadobutrol can be useful in a wide range of MRI applications, including (but not limited to): hepatic imaging, pelvic imaging, cardiac imaging, brain and spine imaging, and musculoskeletal imaging.

Physics and Imaging Technology: MRI
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Article information

rID: 31782
Synonyms or Alternate Spellings:
  • Gadavist
  • Gadovist

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