Gadobutrol

Gadobutrol (also known as Gadovist/GadavistTM) is an extracellular intravenous contrast agent used in magnetic resonance imaging.

  • cyclic, nonionic molecule 
  • 100% renally excreted
  • T1 relaxivity @ 1.5 T: 4.9-5.5 (slightly higher than other extracellular contrast agents)
  • concentration: 1.0 mmol/ml
  • recommended dosage: 0.1 mmol/kg

Of note, gadobutrol's standard concentration (1 mmol/ml) is 2x - 4x that of other commercially available gadolinium chelates, and the smaller injection volume should be considered when planning the timing of the arterial phase in postcontrast dynamic sequences.

Indications

As an extracellular contrast agent, gadobutrol can be useful in a wide range of MRI imaging applications, including (but not limited to): hepatic imaging, pelvic imaging, cardiac imaging, brain and spine imaging, and musculoskeletal imaging.


MRI physics
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Article Information

rID: 31782
Section: Physics
Synonyms or Alternate Spellings:
  • Gadavist
  • Gadovist

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