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Gadobutrol (also known as Gadovist/Gadavist) is an extracellular intravenous contrast agent used in magnetic resonance imaging.
cyclic, non-ionic molecule
100% renally excreted
T1 relaxivity at 1.5 T: 4.9-5.5 (slightly higher than other extracellular contrast agents)
concentration: 1.0 mmol/mL
recommended dosage: 0.1 mmol/kg
Of note, gadobutrol's standard concentration (1 mmol/mL) is 2-4 times greater than that of other commercially-available gadolinium chelates, and the smaller injection volume should be considered when planning the timing of the arterial phase in post-contrast dynamic sequences.
As an extracellular contrast agent, gadobutrol can be useful in a wide range of MRI applications, including (but not limited to): hepatic imaging, pelvic imaging, cardiac imaging, brain and spine imaging, and musculoskeletal imaging.