Gadoterate meglumine

Dr Dan J Bell and Dr Matt A. Morgan et al.

Gadoterate meglumine (also known by the tradename DotaremTM) is an intravenous extracellular MRI contrast agent.

  • cyclic, ionic molecule 
  • 100% renally excreted
  • T1 relaxivity at 1.5 T: 3.4-3.8 (slightly lower than other extracellular contrast agents)
  • concentration: 0.5 mmol/ml
  • recommended dosage: 0.1 mmol/kg

It is considered a high-stability agent, and is considered a good choice for patients with lower GFRs (see: nephrogenic systemic fibrosis)

Indications
  • abdominal or pelvic mass
  • HCC screening or evaluation
  • evaluation of hepatic haemangioma
  • cardiac MRI
  • mediastinal MRI
Physics and Imaging Technology: MRI
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Article information

rID: 33803
Synonyms or Alternate Spellings:
  • Dotarem

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