Gallium 67 scintigraphy

Gallium 67 is a photon-emitting radiotracer which is used in the form of various salts like citrate and nitrate. Once administered, imaging may consist of planar (2 dimensional) , SPECT, and SPECT/CT acquisitions. Once injected it binds to plasma proteins (especially transferrin), and has a predilection to sites of inflammation. It binds to inflammatory proteins and thus it pools up at the sites of various inflammatory and granulomatous reactions.

  • emits a spectrum of gamma rays (93, 185, 288, 394 KeV energy)
  • half life is about 78 hours
  • critical organ: colon
  • normal distribution is seen in the liver, bone marrow and spleen
  • given in IV form, dose is about 3-6 mCi (millicurie) 
  • imaging can be done at 24, 48, and 72 hours.
  • study may include planar, SPECT and SPECT/CT imaging
  • has largely been replaced by 18-F FDG PET/CT imaging which has the advantage of earlier scan, better image quality, and SUV quantification
  • better in evaluation of spinal infection than other tagged WBC radiotracers
  • gallium citrate usually shows a negative scan earlier than other radionuclide like technetium used in bone scanning
  • higher radiation dose than other WBC radiotracers 
  • poor image quality
  • cannot differentiate between osteomyelitis and cellulitis
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Article information

rID: 25437
Section: Physics
Synonyms or Alternate Spellings:
  • Gallium scan
  • Gallium scintigraphy
  • Gallium 67 scan

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