Gamma-aminobutyric acid (GABA) peak

Gamma-aminobutyric acid (GABA) is one of the compounds examined in MR spectroscopy and is the principle inhibitory neurotransmitter of the central nervous system 1. It resonates at approximately 2.2-2.4 ppm chemical shift overlapping the peaks of glutamate and glutamine 1-3. It is not routinely possible to separate it from the other peaks in this region of the spectrum.  

Changes in concentration of GABA has been reported in a number of clinical scenarios, although day to day application is limited 2

MR spectroscopy
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Article Information

rID: 27825
Section: Physics
Synonyms or Alternate Spellings:
  • GABA peak
  • gamma-aminobutyric acid
  • Gamma-aminobutyric acid (GABA)

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