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Gamma Knife

Dr Daniel J Bell et al.

Gamma Knife®, also known as Gamma Knife radiosurgery (GKRS), is a form of radiosurgery historically employing 201 cobalt-60 sources arranged in a hemispheric array. The latest system, the Gamma Knife Perfexion™, uses 192 cobalt-60 sources 1. The emitted gamma rays are focused on a target point which is used to treat brain lesions. It employs a standard stereotactic frame to ensure accurate targeting of the emitted beams to a precise location. Gamma Knife systems are solely manufactured by Elekta AB, a Swedish company, that specializes in radiation therapy systems. 

History and etymology

Gamma knife was invented by Lars Leksell, a pioneering Swedish neurosurgeon, in collaboration with a radiation biologist, Borje Larsson, and their first system was available in 1951. Lars Leksell and his son, Laurent Leksell, founded Elekta in 1972 to manufacture Gamma Knife systems 2.

Radiation therapy

Article information

rID: 67451
Tag: refs, refs
Synonyms or Alternate Spellings:
  • Gamma Knife Perfexion
  • Gamma Knife radiosurgery (GKRS)
  • Gamma-knife

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