Gardner syndrome

Gardner syndrome is one of the polyposis syndromes. It is characterized by:

Other abnormalities include:

Pathology

There is an autosomal dominant inheritance in the FAP gene (chromosome 5q) in a majority of patients but with 20% of cases resulting from new mutations. Extracolonic features often precede the diagnosis of colonic polyps. 

History and etymology

First described in 1953 by Gardner and Richards 3.

Share article

Article information

rID: 1370
Tag: cases
Synonyms or Alternate Spellings:
  • Gardner's syndrome

Support Radiopaedia and see fewer ads

Cases and figures

  • Case 1: duodenal polyps and osteomas, proven syndrome
    Drag here to reorder.
  • Case 2: multiple osteomas and supernumerary teeth
    Drag here to reorder.
  • Case 3
    Drag here to reorder.
  • Updating… Please wait.

     Unable to process the form. Check for errors and try again.

     Thank you for updating your details.