Gasperini syndrome
Gasperini syndrome is a rare pontine stroke syndrome that involves the caudal pontine tegmentum.
On this page:
Clinical presentation
Classically, the syndrome presents with 1-3:
- involvement of the CN V nucleus (sensory nucleus of the trigeminal nerve): ipsilateral facial sensory loss
- involvement of the CN VI nucleus (abducens nucleus): ipsilateral impaired eye abduction
- involvement of the CN VII nucleus (facial nucleus): ipsilateral facial palsy and hyperacusis
- involvement of the CN VIII nucleus: vertigo and ipsilateral nystagmus
- involvement of the spinothalamic tract: contralateral hemi-sensory impairment
Pathology
A lesion of the caudal pons tegmentum is usually caused by an ischemic stroke, usually due to occlusion of either pontine branches of the basilar artery or the long circumferential branch of the anterior inferior cerebellar artery 1,2, but can also be seen due to demyelination or hemorrhage 3.
Radiographic features
Lesions are in the caudal pons tegmentum with imaging characteristics depending on underlying cause 2,3.
History and etymology
The syndrome was first described by Ubaldo Gasperini (1880-1918), an Italian physician, in 1912 1,4.
Related Radiopaedia articles
Stroke and intracranial haemorrhage
-
stroke and intracranial hemorrhage
- code stroke CT (an approach)
-
ischemic stroke
- general discussions
- scoring and classification systems
- signs
- by region
- hemispheric infarcts
- frontal lobe infarct
- parietal lobe infarct
- temporal lobe infarct
- occipital lobe infarct
- alexia without agraphia syndrome: PCA
- cortical blindness syndrome (Anton syndrome): top of basilar or bilateral PCA
- Balint syndrome: bilateral PCA
- lacunar infarct
-
thalamic infarct
- Déjerine-Roussy syndrome (thalamic pain syndrome): thalamoperforators of PCA
- top of the basilar syndrome
- striatocapsular infarct
- cerebellar infarct
-
brainstem infarct
- midbrain infarct
- Benedikt syndrome: PCA
- Claude syndrome: PCA
- Nothnagel syndrome: PCA
- Weber syndrome: PCA
- pontine infarct
- Brissaud-Sicard syndrome
- facial colliculus syndrome
- Gasperini syndrome: basilar artery or AICA
- inferior medial pontine syndrome (Foville syndrome): basilar artery
- lateral pontine syndrome (Marie-Foix syndrome): basilar artery or AICA
- locked-in syndrome: basilar artery
- Millard-Gubler syndrome: basilar artery
- Raymond syndrome: basilar artery
- medullary infarct
- Babinski-Nageotte syndrome
- hemimedullary syndrome (Reinhold syndrome)
- lateral medullary stroke syndrome (Wallenberg syndrome)
- medial medullary syndrome (Déjerine syndrome)
- midbrain infarct
- acute spinal cord ischemia syndrome
- hemispheric infarcts
- by vascular territory
- treatment options
- complications
-
intracranial hemorrhage
-
intra-axial hemorrhage
- signs and formulas
- ABC/2 (volume estimation)
- CTA spot sign
- swirl sign
- by region or type
- signs and formulas
- extra-axial hemorrhage
-
intra-axial hemorrhage
Unable to process the form. Check for errors and try again.