Gastro-oesophageal junction

Last revised by Bálint Botz on 23 Feb 2021

The gastro-oesophageal junction (GOJ) (also known as the oesophagogastric junction) is the part of the gastrointestinal tract where the oesophagus and stomach are joined.

The GOJ is normally mostly intra-abdominal and is 3-4 cm in length. To some extent, the oesophagus slides in and out of the abdomen during respiration and when there is elevation of intra-abdominal pressure.

It is comprised of two histologically distinct areas:

  • stratified squamous epithelium (same as the oesophageal folds superiorly)
  • columnar epithelium (same as the gastric rugae inferiorly)

Where these two distinct areas join, there is an abrupt but non-linear change in the mucosal layer: this is called the Z-line. The non-linear, zig zagging nature of the Z-line explains that the GOJ can be several centimetres in length, while the histological transition from oesophageal folds to gastric rugae is abrupt.

Unfortunately the GOJ is not directly visualised on plain film, which is of particular importance during the assessment of the position of nasogastric tubes. According to one study tube tips below the level of the disc between the 11th and 12th thoracic vertebra and/or more than 16 mm from the left side of the spine can be considered to be in the stomach 2. However for practical purposes the tube tip should ideally be at least 10 cm beyond from the expected location of the GOJ.

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